Job Description

Job Title: Director, Portfolio and Project Management

Department: Portfolio and Project Management

Location: Hybrid or Remote

About SiteOne Therapeutics

SiteOne Therapeutics is a clinical-stage biopharmaceutical company advancing a novel class of highly selective small molecule inhibitors targeting NaV1.7, NaV1.8, and other ion channels to treat pain, cough and other conditions involving hyperexcitability of the peripheral nervous system. Since its inception, SiteOne has been dedicated to the development of safe and effective pain therapeutics without the significant addiction potential and side effects of opioids. The company is also advancing additional novel drug candidates that exhibit precise selectivity for individual ion channel subtypes to treat other sensory hyperexcitability disorders such as chronic cough and chronic ocular surface pain.

Position Summary

The Director of Portfolio and Project Management (PPM) will have accountability for implementing best practices and tools for key program team processes, including planning, decision-making, communication, and risk management. This individual will work closely with senior leadership to ensure team performance and facilitate the development of both individual leaders and cross-functional teams within a matrixed environment. The Director will lead portfolio-level activities such as resource planning, activity modeling, and contribute to setting and reporting on corporate goals. The Director of PPM will report to the VP of PPM.

Responsibilities

Drive Program Planning: Lead the planning and execution of cross-functional program activities, including resource allocation, financial assessments, and capacity planning.

Manage Program Teams: Oversee the operational execution of program teams, ensuring effective decision-making, risk management, and issue resolution processes.

Team Leadership: Mentor, guide, and develop project managers and cross-functional team members, ensuring strong collaboration and accountability.

Improve Processes: Identify opportunities for process improvements and implement best practices to increase efficiency, communication, and alignment across the organization.

Manage Reporting: Lead the preparation of program and portfolio reports, including dashboards, status updates, and presentations to senior leadership and key stakeholders.

Collaborate with Leadership: Partner with Project Team Leaders and functional leaders to align team goals with the organization’s strategic objectives.

Stakeholder Communication: Ensure consistent and effective communication across teams, managing expectations and aligning stakeholders on program progress.

Education & Experience Requirements

Education:

Successful candidates will have a bachelor’s degree from an accredited college or university, advanced degree preferred. PMP certification is preferred.

Background and Experience:

8+ years of experience in program or project management within the pharmaceutical or biotechnology industry.

Strong knowledge of program management tools and methodologies (e.g., Smartsheet, Microsoft Project).

Proven ability to lead cross-functional teams, manage complex projects, and drive continuous improvement.

Excellent communication, leadership, and relationship management skills.

As a small biotech company, qualities that we seek include:

• Versatility: ability to handle multiple responsibilities and where different hats as needed in a dynamic work environment.
• Initiative: proactive and self-motivated, capable of taking initiative to solve problems and drive projects forward proactively
• Hands-on Experience: Practical, hands-on experience in their function while being able to maintain overall strategic view
• Flexibility: need to be flexible and adaptable to changing priorities and tasks, willing to pitch in wherever needed.
• Adaptability: able to adapt quickly to new challenges, technologies, and ways of working

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